BALB/c Mouse

The BALB/c is a good general-use strain used for a variety of research purposes. This subline is the most widely-used for production of monoclonal antibodies by hybridoma technique. The best ascites tumour growth is obtained by using the same subline for fusion and ascites production. 

It exhibits good breeding performance and has a long reproductive lifespan Plasmacytomas induced by injection of mineral oil from the basis for the production of monoclonal antibodies by hybridoma technique. BALB/c is widely used for this purpose. For antibody production in ascites, F1 hybrids of BALB/c and an outbred Swiss mouse (i.e. NMRI) may be advantageous.